is single row update improved with function

I must update 3M of 100M records, with tuple specific modifications.  I can generate the necessary sql, but I’m
wonderingif files of simple update statements affecting a single row is more effective than files of a function call
doingthe same update given the necessary values, including where clause restrictions?  The query plan set by the first
shouldbe decent for the remainder. 

Alternatively, would a bulk load into a table of replacement values and join info be the fastest way?

Either way I can break the updates into roughly 393 transactions (7500 rows affected per tx) or 8646 transactions (350
rows per tx) if less is more in this world. 

I’ll be the only user during this work.

OS=centos 7, 4core virtual 64G memory; pg=10.0;